Cytoskeleton and Extracellular Matrix
The cytoskeleton acts as a cellular scafforld within a cell and plays an important role in many processes such as cell motility and cell division. Many cytoskeletal proteins interact with proteins of the extracellular matrix (ECM). The ECM is a network of extracellular molecules which provide structural and biochemical support to surrounding. The ECM is vital to cellular processes including proliferation, adhesion, migration, polarity, differentiation, and apoptosis.
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View products: Actin | Matrix Metalloproteases (MMP) | PI3K/Akt/mTOR | Microtubule | ROCK (Rho-kinase)
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ROCK inhibitor Y-27632 (HB2297)
Description:Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.
Purity:>99%
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YM-254890 (HB6283)
Description:Potent Gq/11 signaling inhibitor. Reported as Gq- G-protein inhibitor and broad-spectrum inhibitor for Gq- and Gs-proteins.
Purity:>98%
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YM 298198 hydrochloride (HB0664)
Description:Potent, selective, non-competitive mGlu1 antagonist
Purity:>99%
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Zacopride hydrochloride (HB1694)
Description:Potent 5-HT3 antagonist and 5-HT4 agonist. Also selective IK1 channel agonist.
Purity:>99%
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Zatebradine hydrochloride (HB1151)
Description:HCN channel blocker. Potent, selective bradycardic agent.
Purity:>95%
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ZD 7288 (HB1152)
Description:HCN channel blocker. Modulates sino-atrial node function.
Purity:>98%
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Zebularine (HB1378)
Description:DNA methyltransferase inhibitor. Induces cardiomyocyte differentiation in MSCs.
Purity:>99%
