Irreversible and selective caspase 3 inhibitor (IC50 = 0.13 µM). Cell permeable. Exhibits no activity at cathespin B and cathespin L. Displays neuroprotective properties and inhibits apoptosis.
Solubility & Handling
Solubility overview
Soluble in DMSO (13.37mg/ml)
Storage instructions
-20°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line. Cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3.
Brockstedt E et al (1998) J Biol Chem 273(43) : 28057-64.
Understanding purity and quality - a guide for life scientists