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Biological Data
| Biological description | Cell permeable caspase 3 specific inhibitor. Attenuates β-catenin degradation but does not affect β-catenin and GSK-3β phosphorylation |
Solubility & Handling
| Storage instructions | -20°C (desiccate) |
| Solubility overview | Soluble in DMSO (13.71mg/ml) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | Benzyloxycarbonyl-Asp(OMe)-Gln-Met-Asp(OMe)-fluoromethylketone |
| Molecular Formula | C29H40FN5O11S |
| PubChem identifier | 644197 |
| SMILES | [H]N([C@@H](CC(=O)OC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)C(=O)OCC1=CC=CC=C1 |
| InChiKey | QFITYVNVMNJELE-TUFLPTIASA-N |
References for Z-DQMD-FMK
References are publications that support the biological activity of the product
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Photodynamic therapy in combination with talaporfin sodium induces mitochondrial apoptotic cell death accompanied with necrosis in glioma cells.
Miki Y et al (2013) Biol Pharm Bull 36(2) : 215-21. -
Inhibiting caspase-3 activity blocks beta-catenin degradation after focal ischemia in rat.
Zhang H et al (2008) Neuroreport 19(8) : 821-4.
Cell permeable caspase 3 specific inhibitor
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