Cytokines, chemokines & NF-κB/I-κB

Water soluble Toll-like receptor 7 (TLR7) agonist. Stimulates cytokine production.

Calcium ionophore. Stimulates cytokine production.

Calcium ionophore. Stimulates cytokine production.

Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.

Protein transport inhibitor. Commonly used in cytokine staining.

PKC activator. Widely used for THP-1 cell differentiation and with ionomycin for stimulating cytokine production

TNFα-induced NF-κB activation inhibitor.

Selective IKKα and IKKβ kinase activity inhibitor. NF-κB inhibitor.

Apoptosis inducer. Modulates NF-κB activation.

Selective, cell permeable and irreversible MALT1 inhibitor