Cytokine Storm / Immune response signaling

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Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.

View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling

Items 21-30 of 142

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  1. Butyrolactone I (HB3820)

    Description:

    Potent, selective CDK1, CDK2 and CDK5 inhibitor

    Purity:

    >97%

    Pack:
    1mg
    Price:
    $549
    Qty:
  2. Calphostin C (HB0160)

    Description:

    Potent, selective PKC inhibitor. Also antagonizes the Tcf/β-catenin complex

    Purity:

    >95%

    Pack:
    100μg
    Price:
    $232
    Qty:
    Pack:
    1mg
    Price:
    $1,176
    Qty:
  3. Cercosporin (HB3826)

    Description:

    Potent and specific PKC inhibitor

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $549
    Qty:
  4. Pack:
    5mg
    Price:
    $135
    Qty:
    Pack:
    25mg
    Price:
    $547
    Qty:
  5. Pack:
    5mg
    Price:
    $127
    Qty:
    Pack:
    25mg
    Price:
    $438
    Qty:
  6. CHIR 99021 (HB1261)

    Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $48
    Qty:
    Pack:
    2mg
    Price:
    Qty:
    Pack:
    5×2mg
    Price:
    $180
    Qty:
    Pack:
    10mg
    Price:
    $175
    Qty:
    Pack:
    5mg
    Price:
    $112
    Qty:
    Pack:
    25mg
    Price:
    $427
    Qty:
    Pack:
    50mg
    Price:
    $727
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $121
    Qty:
  7. Description:

    Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons. Water soluble.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $220
    Qty:
    Pack:
    50mg
    Price:
    $879
    Qty:
  8. Pack:
    1mg
    Price:
    $512
    Qty:
    Pack:
    3mg
    Price:
    $1,437
    Qty:
  9. Pack:
    10mg
    Price:
    $127
    Qty:
    Pack:
    50mg
    Price:
    $572
    Qty:
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