CMIQ

Name: CMIQ
SKU: HB0077
Price: 512 USD
Availability: InStock

(HB0077)

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Technical documents: Datasheet

Product overview

Name

CMIQ

Purity

>95%

Description

Potent, selective PKA inhibitor

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) References (3)

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Biological Data

Biological description

Potent and selective protein kinase A (PKA) inhibitor (IC₅₀ = 30 nM ). Membrane permeable. Blocks ATP-binding site of PKA. Restores morphine-related behaviours in morphine tolerance.

Solubility & Handling

Storage instructions

+4°C

Solubility overview

Soluble in DMSO (50mg/ml)

Important

This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

More Info

Dilution

More Info

Chemical Data

Purity

>95%

Chemical name

PKA Inhibitor XI

Molecular Weight

168.2

Chemical structure

Molecular Formula

C₁₁H₈N₂

CAS Number

161468-32-2

Technical guides

Understanding purity and quality - a guide for life scientists (159.4 KB)

References for CMIQ

References are publications that support the biological activity of the product

PKC and PKA inhibitors reinstate morphine-induced behaviors in morphine tolerant mice.
Smith FL et al (2006) Pharmacol Res 54(6) : 474-80.
Read more (PubMedID: 17056270)
Epac mediates a cAMP-to-PKC signaling in inflammatory pain: an isolectin B4(+) neuron-specific mechanism.
Hucho TB et al (2005) J Neurosci 25(26) : 6119-26.
Read more (PubMedID: 15987941)
Selective inhibition of cyclic AMP-dependent protein kinase by isoquinoline derivatives.
Lu ZX et al (1996) Biol Chem Hoppe Seyler 377(6) : 373-84.
Read more (PubMedID: 8839983)

Potent, selective PKA inhibitor

Order: HB0077
Pack	Price	Qty
1mg	$512
3mg	$1,437

CMIQ

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for CMIQ

PKC and PKA inhibitors reinstate morphine-induced behaviors in morphine tolerant mice.

Epac mediates a cAMP-to-PKC signaling in inflammatory pain: an isolectin B4(+) neuron-specific mechanism.

Selective inhibition of cyclic AMP-dependent protein kinase by isoquinoline derivatives.

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CMIQ

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for CMIQ

PKC and PKA inhibitors reinstate morphine-induced behaviors in morphine tolerant mice.

Epac mediates a cAMP-to-PKC signaling in inflammatory pain: an isolectin B4(+) neuron-specific mechanism.

Selective inhibition of cyclic AMP-dependent protein kinase by isoquinoline derivatives.

About you

Tell us about your publication!

Captcha

About you

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New Products in this Area