My Cart
My account
Menu
Main Menu

CGP 74514A

(HB0186)
Be the first to add a publication
Technical documents: Datasheet
Be the first to review this product
Add to Wish List

Product overview

Name CGP 74514A
Description Selective CDK1 inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3)
Write Your Own Review
You're reviewing:CGP 74514A
Rate this item:

Biological Data

Biological description Selective CDK1 inhibitor. Shows anti-tumor activity, induces apoptosis and mitochondrial damage.

Solubility & Handling

Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Chemical name 2-N-(2-aminocyclohexyl)-6-N-(3-chlorophenyl)-9-ethylpurine-2,6-diamine
Molecular Weight 385.89
Chemical structure CGP 74514A Chemical Structure
Molecular Formula C19H24ClN7
CAS Number 1173021-98-1
PubChem identifier 4644095
SMILES CCN1C=NC2=C1N=C(N=C2NC3=CC(=CC=C3)Cl)NC4CCCCC4N

References for CGP 74514A

References are publications that support the biological activity of the product

  • The cytotoxic effect of emetine and CGP-74514A studied with the hollow fiber model and ArrayScan assay in neuroendocrine tumors in vitro.

    Larsson DE et al (2012) Anticancer Agents Med Chem 12(7) : 783-90.
    Read more (PubMedID: 22263790)

  • CDK1 differentially regulates G-overhang generation at leading- and lagging-strand telomeres in telomerase-negative cells in G2 phase.

    Dai X et al (2012) Cell Cycle 11(16) : 3079-86.
    Read more (PubMedID: 22871736)

  • Induction of apoptosis in human leukemia cells by the CDK1 inhibitor CGP74514A.

    Dai Y et al (2002) Cell Cycle 1(2) : 143-52.
    Read more (PubMedID: 12429924)

3 Item(s)

Grouped product items
Order: HB0186
Pack PriceQty
5mg
$139
25mg
$563
Selective CDK1 inhibitor
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

Contact Us

Call 609-683-7500
Fax 609-228-4994

customercare-usa@hellobio.com