Antagonists & inhibitors
An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.
SKF 83566 hydrobromide (HB1863)
Description:Potent, selective D1-like receptor antagonist
Purity:>98%
SKF 89976A hydrochloride (HB0976)
Description:Potent, selective, competitive GAT-1 GABA uptake inhibitor
Purity:>99%
Skyrin (HB4088)
Description:Selective glucagon receptor antagonist. Non-peptidic anti-diabetic agent
Purity:>97%
Spiperone hydrochloride (HB1656)
Description:Selective D2-like receptor antagonist. 5-HT2A antagonist.
Purity:>98%