Glutamate uptake & transport
Glutamate transport is mediated by a family of transmembrane proteins known as glutamate transporters, or excitatory amino acid transporters (EAATs). EAATs are sodium- and potassium-dependent members of the Solute Carrier Family 1 (SLC1). The five EAAT subtypes are EAAT1 (Excitatory amino acid transporter 1 / SLC1A3) , EAAT2 (Excitatory amino acid transporter 2 / SLC1A2), EAAT3 (Excitatory amino acid transporter 3 / SLC1A1), EAAT4 (Excitatory amino acid transporter 4 / SLC1A6) and EAAT5 (Excitatory amino acid transporter 5 / SLC1A7). Researchers can save up to 50% on EAAT inhibitors, activators and modulators from Hello Bio - they are up to half the price of other suppliers.
YC-1 (HB3521)
Description:Guanylyl cyclase activator. Also induces G1 cell cycle arrest.
Purity:>98%
YM-254890 (HB6283)
Description:Potent Gq/11 signaling inhibitor. Reported as Gq- G-protein inhibitor and broad-spectrum inhibitor for Gq- and Gs-proteins.
Purity:>98%
YM 298198 hydrochloride (HB0664)
Description:Potent, selective, non-competitive mGlu1 antagonist
Purity:>99%
Yoda2 (KC289) (HB9134)
Description:Novel, selective Piezo1 channel activator. Improved efficacy, potency and solubility compared to Yoda1.
Zacopride hydrochloride (HB1694)
Description:Potent 5-HT3 antagonist and 5-HT4 agonist. Also selective IK1 channel agonist.
Purity:>99%
Zatebradine hydrochloride (HB1151)
Description:HCN channel blocker. Potent, selective bradycardic agent.
Purity:>95%
ZD 7288 (HB1152)
Description:HCN channel blocker. Modulates sino-atrial node function.
Purity:>98%