Transporters
Transporters are integral transmembrane proteins involved in the movement of ions, small molecules, peptides, lipids or macromolecules, such as another protein, across a biological membrane. The energy required for active transport processes is obtained by hyrdolyzing ATP or by utilising ion gradients. The three major classes of ATP-driven transporters are: P-type ATPases (eg. Ca2+-ATPases and Na+,K+-ATPases); F-type or V-type ATPases and ATP-binding cassette transporters. The solute carrier family of transporters include the biogenic amine transporters (NET, DAT and SERT) the Na+/H+ exchanger, glutamate transporters (EAAT) and GABA transporters (GAT). Researchers can save up to 50% on transporter blockers and inhibitors from Hello Bio – they are up to half the price of other suppliers and have been reviewed and cited by researchers worldwide.
View transporter products: Cannabinoid | Dopamine | GABA | Glutamate | Glycine | Monoamine | Multidrug Transporter | Na+ / Ca2+ exchangers | Na+ / H+ exchangers | Norepinephrine | Serotonin (5-HT)
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SNX 482 (HB1235)
Description:Reported to be a potent, selective Cav2.3 (R-type) channel blocker
Purity:>95%
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Sodium butyrate (HB1399)
Description:HDAC inhibitor. Directs mESC differentiation into hepatocytes.
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SP600125 (HB2234)
Description:Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.
Purity:>98%
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Spadin (HB5438)
Description:Potent TREK-1/ K2P2.1 channel blocker. Shows fast-acting antidepressant effects.
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Spiperone hydrochloride (HB1656)
Description:Selective D2-like receptor antagonist. 5-HT2A antagonist.
Purity:>98%
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Spironolactone (HB2799)
Description:Mineralocorticoid and androgen receptor antagonist
Purity:>98%
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Splitomicin (HB4091)
Description:Potent,selective, cell permeable yeast NAD+-dependent HDAC Sir2p inhibitor
Purity:>98%
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