Group I (mGlu5, mGlu1)
Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
Ziprasidone hydrochloride (HB1753)
Description:5-HT2A and D2 antagonist. Atypical antipsychotic.
Purity:>99%
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Z-Leu-Leu-Leu-B(OH)2 (MG-262) (HB4134)
Description:Highly potent, selective, cell permeable proteasome inhibitor. More potent than MG-132.
Purity:>95%
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Z-Leu-Leu-Nva-CHO (HB4136)
Description:Potent, reversible and cell permeable proteasome inhibitor
Purity:>95%
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Z-Leu-Leu-Phe-CHO (HB4137)
Description:Reversible and cell permeable proteasome inhibitor
Purity:>95%
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ZM 447439 (HB1444)
Description:Potent, selective, ATP-competitive Aurora kinase B inhibitor
Purity:>99%
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Zoledronic acid (HB0674)
Description:Highly potent bisphosphonate, shows variety of biological actions
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Zoniporide dihydrochloride (HB1137)
Description:Potent, selective Na+ / H+ exchanger-1 inhibitor
Purity:>99%
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