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Group I (mGlu5, mGlu1)
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Group I metabotropic glutamate receptors (mGlu1, mGlu5) are coupled with phospholipase C (PLC) via Gq proteins; activation causes increased levels of IP3 and diacylglycerol, with intracellullar Ca2+ release and protein kinase C (PKC) activation. Group I receptors are predominantly located post synaptically. Researchers can save 50% on group I metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.
Zotepine (HB1778)
Description:5-HT2A and dopamine D2 receptor antagonist. Atypical antipsychotic.
Purity:>99%
Z-VAD-(OMe)-FMK (HB1319)
Description:Irreversible, cell permeable, broad spectrum caspase inhibitor.
Purity:>95%
Z-VRPR-FMK (HB4138)
Description:Selective, cell permeable and irreversible MALT1 inhibitor
Purity:>90%