Product overview

Name Z-Leu-Leu-Nva-CHO
Purity >95%
Description Potent, reversible and cell permeable proteasome inhibitor
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Biological Data

Biological description Potent, reversible and cell permeable proteasome inhibitor. Specifically inhibits the chymotrypsin-like activity of the proteasome. Calpain and cathepsin inhibitor. Apoptosis inducer in Rat-1 and PC12 cells via a p53-dependent pathway. Autophagy activator.

Solubility & Handling

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >95%
Molecular Weight 461.6
Chemical structure Z-Leu-Leu-Nva-CHO (MG-115) [133407-86-0] Chemical Structure
CAS Number 133407-86-0
Appearance Solid lyophilized powder