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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 661-670 of 747

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  1. Thiazovivin (HB3240)

    Description:

    Rock inhibitor. Improves hESCs survival and fibroblast reprogramming efficiency and iPSCs induction.

    Purity:

    >97%

    Thiazovivin
    Pack:
    10mg
    Price:
    $405
    Qty:
    Pack:
    25mg
    Price:
    $645
    Qty:
    Supporting Docs Add to Favorites

  2. L-threo-Sphingosine C-18 (HB0388)

    Description:

    PKC inhibitor

    Purity:

    >98%

    L-threo-Sphingosine C-18
    Pack:
    50mg
    Price:
    $1,136
    Qty:
    Supporting Docs Add to Favorites

  3. Tiagabine hydrochloride (HB0978)

    Description:

    Selective GAT-1 GABA uptake inhibitor

    Purity:

    >99%

    Tiagabine hydrochloride
    Pack:
    10mg
    Price:
    $78
    Qty:
    Pack:
    50mg
    Price:
    $316
    Qty:
    Supporting Docs Add to Favorites

  4. Topiramate (HB0618)

    Description:

    Selective GluK1 kainate receptor antagonist

    Purity:

    >99%

    Topiramate
    Pack:
    100mg
    Price:
    $792
    Qty:
    Supporting Docs Add to Favorites

  5. Torcetrapib (HB0879)

    Description:

    Cholesteryl ester transfer protein inhibitor

    Purity:

    >99%

    Torcetrapib
    Pack:
    10mg
    Price:
    $162
    Qty:
    Pack:
    50mg
    Price:
    $651
    Qty:
    Supporting Docs Add to Favorites

  6. Torin 1 (HB2253)

    Description:

    Potent, selective mTOR inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $153
    Qty:
    Pack:
    50mg
    Price:
    $447
    Qty:
    Supporting Docs Add to Favorites

  7. Torin 2 (HB2254)

    Description:

    Potent, selective mTOR inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $447
    Qty:
    Supporting Docs Add to Favorites

  8. TPh A (HB4111)

    Description:

    Nuclear protein pirin inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $58
    Qty:
    Pack:
    5mg
    Price:
    $146
    Qty:
    Supporting Docs Add to Favorites

  9. TPP-1 (HB6617)

    Description:

    PD-1/PD-L1 interaction inhibitor

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $200
    Qty:
    Supporting Docs Add to Favorites

  10. TRAM 34 (HB1058)

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    Description:

    Potent, selective KCa3.1 channel blocker

    Purity:

    >99%

    TRAM 34
    Pack:
    10mg
    Price:
    $111
    Qty:
    Pack:
    25mg
    Price:
    $218
    Qty:
    Supporting Docs Add to Favorites
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Biological action
  1. Modulator
  2. Agonist
  3. Antagonist
  4. Activator
  5. Inhibitor
  6. Blocker
  7. NAM
  8. Dyes & stains
Applications
  1. Antineoplastic Agent
  2. Cell Culture
  3. Selection Agent
Target
  1. Histone H3
  2. mTOR