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L-threo-Sphingosine C-18

(HB0388)
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Product overview

Name L-threo-Sphingosine C-18
Alternative names L-threo-C18-sphingosine
Purity >98%
Description PKC inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (2)
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Biological Data

Biological description Protein kinase C (PKC) inhibitor. D-erythro-sphingosine analog.

Solubility & Handling

Solubility overview Soluble in ethanol
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name (2S,3S,4E)-2-aminooctadec-4-ene-1,3-diol
Molecular Weight 299.5
Chemical structure L-threo-Sphingosine C-18 [25695-95-8] Chemical Structure
Molecular Formula C18H37NO2
CAS Number 25695-95-8

References for L-threo-Sphingosine C-18

References are publications that support the biological activity of the product

  • Sphingolipid biosynthesis in cultured neurons. Down-regulation of serine palmitoyltransferase by sphingoid bases.

    Mandon EC et al (1991) Eur J Biochem 198(3) : 667-74.
    Read more (PubMedID: 1646717)

  • Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds.

    Merrill AH Jr et al (1989) Biochemistry 28(8) : 3138-45.
    Read more (PubMedID: 2742830)

2 Item(s)

Grouped product items
Order: HB0388
Pack PriceQty
50mg
$1,170
PKC inhibitor
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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