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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
- Description:
Broad spectrum glutamate antagonist
Purity:>99%
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Gatifloxacin (HB3263)
Description:Antibiotic; bacterial type II topoisomerase inhibitor. Activates ESC short term renewal.
Purity:>98%
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GBR 12909 dihydrochloride (HB1812)
Description:Potent, competitive dopamine uptake inhibitor
Purity:>98%
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Geldanamycin (HB3311)
Description:Selective Hsp90 inhibitor. Breast cancer stem cell inhibitor.
Purity:>98%
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