DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 1-10 of 17

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  1. Clozapine (HB1607)

    1  Review
    Top Reviews:
    100% of 100
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    Description:

    Prototypic, atypical antipsychotic, binds to both serotonin and dopamine receptors

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $73
    Qty:
    Pack:
    500mg
    Price:
    $394
    Qty:
  2. 3  Reviews
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    100% of 100
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    Description:

    Water soluble prototypic, atypical antipsychotic. Binds to both serotonin and dopamine receptors.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $44
    Qty:
    Pack:
    50mg
    Price:
    $117
    Qty:
  3. 8  Reviews
    Top Reviews:
    96% of 100
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    Description:

    Prototypical DREADD activator. Clozapine metabolite.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $74
    Qty:
    Pack:
    10mg
    Price:
    $107
    Qty:
    Pack:
    25mg
    Price:
    $241
    Qty:
    Pack:
    100mg
    Price:
    $745
    Qty:
  4. 40  Reviews
    Top Reviews:
    99% of 100
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    Description:

    Dihydrochloride salt of CNO - the prototypical DREADD activator

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $60
    Qty:
    Pack:
    10mg
    Price:
    $89
    Qty:
    Pack:
    25mg
    Price:
    $216
    Qty:
    Pack:
    100mg
    Price:
    $675
    Qty:
    Pack:
    1g
    Price:
    $4,210
    Qty:
  5. Description:

    Potent, selective and metabolically stable hM3Dq and hM4Di muscarinic DREADD actuator.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $68
    Qty:
    Pack:
    10mg
    Price:
    $114
    Qty:
    Pack:
    25mg
    Price:
    $157
    Qty:
    Pack:
    100mg
    Price:
    $495
    Qty:
  6. 1  Review
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    100% of 100
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    Description:

    Potent, selective and metabolically stable hM3Dq and hM4Di muscarinic DREADD actuator. Water soluble.

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $73
    Qty:
    Pack:
    10mg
    Price:
    $120
    Qty:
    Pack:
    25mg
    Price:
    $166
    Qty:
    Pack:
    100mg
    Price:
    $523
    Qty:
  7. Description:

    Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $91
    Qty:
    Pack:
    10mg
    Price:
    $137
    Qty:
    Pack:
    25mg
    Price:
    $292
    Qty:
    Pack:
    100mg
    Price:
    $936
    Qty:
  8. 14  Reviews
    Top Reviews:
    99% of 100
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    Description:

    Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant. Water soluble.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $13
    Qty:
    Pack:
    5mg
    Price:
    $73
    Qty:
    Pack:
    10mg
    Price:
    $130
    Qty:
    Pack:
    25mg
    Price:
    $299
    Qty:
    Pack:
    100mg
    Price:
    $1,087
    Qty:
  9. Description:

    Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Freebase.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $85
    Qty:
    Pack:
    10mg
    Price:
    $165
    Qty:
    Pack:
    25mg
    Price:
    $348
    Qty:
    Pack:
    100mg
    Price:
    $1,281
    Qty:
  10. Description:

    Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Water soluble.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $85
    Qty:
    Pack:
    10mg
    Price:
    $165
    Qty:
    Pack:
    25mg
    Price:
    $348
    Qty:
    Pack:
    100mg
    Price:
    $1,281
    Qty:

Items 1-10 of 17

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