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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
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clasto-Lactacystin β-lactone (HB3842)
Description:Potent, selective and irreversible proteasome inhibitor
Purity:>95%
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(±)-Clopidogrel hydrochloride (HB1974)
Description:Selective, irreversible P2Y12 receptor antagonist
Purity:>99%
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CNQX disodium salt (HB0205)
Description:Potent, competitive AMPA / kainate receptor antagonist. Disodium salt.
Purity:>98%
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