DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
CGS 21680 hydrochloride (HB2097)
Description:Prototypic, selective A2A receptor agonist
Purity:>98%
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(R,S)-CHPG sodium salt (HB0034)
Description:Selective mGluR5 agonist. Water soluble sodium salt.
Purity:>99%
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CIQ (HB0197)
Description:GluN2C / GluN2D subunit selective NMDA receptor positive allosteric modulator
Purity:>98%
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Citrinin (HB3839)
Description:Mitochondrial permeability transition pore (MPTP) activator
Purity:>97%
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Clozapine (HB1607)
Description:Prototypic, atypical antipsychotic, binds to both serotonin and dopamine receptors
Purity:>99%
- Description:
Water soluble prototypic, atypical antipsychotic. Binds to both serotonin and dopamine receptors.
Purity:>98%
