Citrinin

(HB3839)
Technical documents: SDS CoA Datasheet
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Product overview

Name Citrinin
Purity >97%
Description Mitochondrial permeability transition pore (MPTP) activator
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Biological Data

Biological description Antibiotic. Antiprotozoal. Antimicrobial. Cytotoxic and genotoxic in various mammalian cells. Mitochondrial permeability transition pore (MPTP) activator. Apoptosis inducer. ERK and JNK signaling pathways activator. Nephrotoxic mycotoxin. Suppresses NO and iNOS expression via inhibition of the JAK/STAT-1alpha and NF-kappaB signaling pathways. Tubulin polymerization and mitotic spindle assembly inhibitor. Increases reactive oxygen species (ROS). Induces cell cycle arrest at the G0/G1 and G2/M phase.

Solubility & Handling

Storage instructions +4°C
Solubility overview

Soluble in methanol and ethanol

Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >97%
Chemical name

(3R,4S)-6-Hydroxy-3,4,5-trimethyl-8-oxo-3,4-dihydroisochromene-7-carboxylic acid

Molecular Weight 250.3
Chemical structure Citrinin [518-75-2] Chemical Structure
Molecular Formula C13H14O5
CAS Number 518-75-2
PubChem identifier 54682830
SMILES C[C@H]1OC=C2C(=O)C(=C(O)O)C(=O)C(=C2[C@@H]1C)C
Source Isolated from Penicillium citrinum
InChiKey CQIUKKVOEOPUDV-IYSWYEEDSA-N
Appearance Yellow solid