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Cinnabarinic acid

(HB0195)
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Technical documents: SDS Datasheet

Product overview

Name Cinnabarinic acid
Purity >98%
Description Selective mGlu4 agonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (3) Reviews References (3) Frequently bought together
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Cinnabarinic acid product vial image | Hello Bio
Cinnabarinic acid product vial image | Hello Bio

Cinnabarinic acid product vial image | Hello Bio

Cinnabarinic acid product vial image | Hello Bio

Biological Data

Biological description Selective mGlu4 receptor agonist. Endogenous metabolite of the kynurenine pathway. Shows no activity at other mGlu receptors. Protective against EAE, a multiple sclerosis model in mice.

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in DMSO (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name 2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid
Molecular Weight 300.22
Chemical structure Cinnabarinic acid [606-59-7] Chemical Structure
Molecular Formula C14H8N2O6
CAS Number 606-59-7
PubChem identifier 114918
SMILES O=C2C(N)=C(C(O)=O)C1=NC3=C(C=CC=C3C(O)=O)OC1=C2
InChiKey FSBKJYLVDRVPTK-UHFFFAOYSA-N

References for Cinnabarinic acid

References are publications that support the biological activity of the product

  • Cinnabarinic acid, an endogenous agonist of type-4 metabotropic glutamate receptor, suppresses experimental autoimmune encephalomyelitis in mice.

    Fazio F et al (2014) Neuropharmacology 81 : 237-43.
    Read more (PubMedID: 24565643)

  • An expanding range of targets for kynurenine metabolites of tryptophan.

    Stone TW et al (2013) Trends Pharmacol Sci 34(2) : 136-43.
    Read more (PubMedID: 23123095)

  • Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type 4 metabotropic glutamate receptors.

    Fazio F et al (2012) Mol Pharmacol 81(5) : 643-56.
    Read more (PubMedID: 22311707)

3 Item(s)

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Grouped product items
Order: HB0195
Pack PriceQty
10mg
$131
50mg
$561
100mg
$860
Selective mGlu4 agonist
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