GluN2C / GluN2D subunit selective NMDA receptor positive allosteric modulator. Causes two-fold increase in receptor channel opening frequency (EC50 values are 2.7 and 2.8 µM for GluN2C and GluN2D respectively). Reduces associated behaviours in schizophrenia models and potentially enhances DA release in Parkinson's disease models.
Solubility & Handling
Soluble in DMSO (100mM) and in ethanol (10mM, sonication)
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.