DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

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    Description:

    Blue fluorescent DNA stain. Nuclear counterstain. 1mg/mL staining solution in water. Solid also available in 10mg and 50mg packs.

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    1mL
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    5mL
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    $516
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  7. Description:

    Selective serotonin reuptake inhibitor (SSRI)

    Purity:

    >99%

    Pack:
    10mg
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    $116
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    $414
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  8. DAPT (HB3345)

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    Description:

    γ-secretase inhibitor and classical notch inhibitor. Induces neuronal differentiation. 3D Growth matrix component and used in cerebral organoid differentiation media.

    Purity:

    >98%

    Pack:
    5mg
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    10mg
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    $168
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    25mg
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    $418
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    50mg
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    $703
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    Pack:
    10mM (1mL in DMSO)
    Price:
    $109
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  9. Description:

    RNA and DNA synthesis inhibitor. Antibiotic.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $116
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    50mg
    Price:
    $242
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  10. Pack:
    1mg
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    5mg
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    $147
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    50mg
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    $773
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