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Biological Data Biological description γ-secretase inhibit and Notch pathway inhibitor. It stimulates iPSC formation from human keratinocytes.
Solubility & Handling Storage instructions -20°C
Solubility overview Soluble in DMSO (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Chemical name N -[(1S )-2-[[(7S )-6,7-Dihydro-5-meth yl-6-oxo-5H -dibenz[b ,d ]azepin-7-yl]amino]-1-methyl -2-oxoethyl]-3,5-difluorobenzeneacetamide
Chemical structure
Molecular Formula C26 H23 F2 N3 O3
PubChem identifier 11454028
SMILES CN1C2=C(C=CC=C2)C3=C(C=CC=C3)[C@H](NC([C@@H](NC(CC4=CC(F)=CC(F)=C4)=O)C)=O)C1=O
InChi InChI=1S/C26H23F2N3O3/c1-15(29-23(32)13-16-11-17(27)14-18(28)12-16)25(33)30-24-21-9-4-3-7-19(21)20-8-5-6-10-22(20)31(2)26(24)34/h3-12,14-15,24H,13H2,1-2H3,(H,29,32)(H,30,33)/t15-,24-/m0/s1
InChiKey QSHGISMANBKLQL-OWJWWREXSA-N
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γ-secretase and Notch pathway inhibitor. Stimulates iPSC formation.