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Biological Data
| Biological description | Selective KDM2/7 JmjC subfamily histone demethylase inhibitor (IC50 values are 0.55, 1.5 and 2.1 µM for PHF8, KDM2A and KDM7A respectively). Plant growth regulator. |
Solubility & Handling
| Storage instructions | Room temperature |
| Solubility overview | Soluble in water (100mM) or DMSO (100mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | 1-(2,2-Dimethylhydrazide)butanedioi c acid |
| Chemical structure | ![Daminozide [1596-84-5] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Daminozide [1596-84-5]") |
| Molecular Formula | C6H12N2O3 |
| SMILES | O=C(NN(C)C)CCC(O)=O |
| InChiKey | NOQGZXFMHARMLW-UHFFFAOYSA-N |
References for Daminozide
References are publications that support the biological activity of the product
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Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases.
Rose NR et al (2012) J Med Chem 55(14) : 6639-43.
Selective KDM2/7 histone demethylase inhibitor
![Daminozide [1596-84-5] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb1404.png "Daminozide [1596-84-5]")
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