DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 911-920 of 1078

Set Descending Direction
  1. SP600125 (HB2234)

    Description:

    Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    Qty:
    Pack:
    50mg
    Price:
    $310
    Qty:
  2. Spadin (HB5438)

    Description:

    Potent TREK-1/ K2P2.1 channel blocker. Shows fast-acting antidepressant effects.

    Pack:
    1mg
    Price:
    $127
    Qty:
  3. Pack:
    50mg
    Price:
    $133
    Qty:
  4. Pack:
    100mg
    Price:
    $72
    Qty:
  5. Pack:
    50mg
    Price:
    $133
    Qty:
  6. Spironolactone (HB2799)

    Description:

    Mineralocorticoid and androgen receptor antagonist

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $54
    Qty:
  7. Splitomicin (HB4091)

    Description:

    Potent,selective, cell permeable yeast NAD+-dependent HDAC Sir2p inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $359
    Qty:
  8. Pack:
    10mg
    Price:
    $246
    Qty:
    Pack:
    50mg
    Price:
    $968
    Qty:
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