DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligands. Researchers can make big savings on Hello Bio's DREADD ligands such as DCZ, CNO and C21, our prices are around 25-50% less than other suppliers.
Further information:Â DREADDs mini-review | Stability of Water-Soluble DREADD Ligands in Solution | CNO (freebase) - stability, solubility and use in the lab
- Description:
Fluorescent M3 muscarinic receptor antagonist
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N-Desmethylclozapine (HB2136)
Description:Biologically active metabolite of clozapine.
Purity:>99%
- Description:
Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant. Water soluble.
Purity:>98%
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DREADD agonist 21 (Compound 21) (HB4888)
Description:Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant.
Purity:>98%
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Iperoxo (HB9785)
Description:Potent muscarinic acetylcholine receptor superagonist. Also binds the hM3R-miniGq DREADD receptor.
Purity:>99%
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PD 102807 (HB1509)
Description:Potent, selective M4 receptor antagonist. Promotes erythroid progenitors expansion.
Purity:>98%
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VU 0357017 hydrochloride (HB1498)
Description:Potent, selective M1 receptor allosteric agonist
Purity:>98%
![CA200887 CellAura fluorescent M<sub>3</sub> antagonist [pirenzepine]](https://cdn.hellobio.com/media/catalog/product/cache/7630ee9852b6c22c7de1165054afc779/h/b/hb7827-ca200887-image1_1.png)
