The store will not work correctly in the case when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
Biological Data Biological description Selective M1 muscarinic receptor agonist. Shows memory enhancing actions.
Solubility & Handling Storage instructions -20°C
Solubility overview Soluble in water (75mM) and in DMSO (50mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use
Chemical Data Chemical name cis -2-Methylspiro[1,3-oxathiolane-5 ,3'-quinuclidine] hydrochloride
Chemical structure
Molecular Formula C10 H17 NOS.HCl
PubChem identifier 9837584
SMILES CC1OC2(CN3CCC2CC3)CS1.Cl
InChi InChI=1S/C10H17NOS.ClH/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11;/h8-9H,2-7H2,1H3;1H
InChiKey SURWTGAXEIEOGY-UHFFFAOYSA-N
References for Cevimeline hydrochloride References are publications that support the biological activity of the product
NGF-dependent neurotrophic-like effects of AF102B, an M1 muscarinic agonist, in PC12M1 cells. Gurwitz D et al (1995) Neuroreport 6(3) : 485-8. L-689,660, a novel cholinomimetic with functional selectivity for M1 and M3 muscarinic receptors. Hargreaves RJ et al (1992) Br J Pharmacol 107(2) : 494-501. (+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3')quinuclidine, an M1 selective cholinergic agonist, attenuates cognitive dysfunctions in an animal model of Alzheimer's disease. Fisher A et al (1991) J Pharmacol Exp Ther 257(1) : 392-403.
Selective M1 receptor agonist
![Cevimeline hydrochloride [107220-28-0] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb1490.png "Cevimeline hydrochloride [107220-28-0]")
Understanding purity and quality - a guide for life scientists