G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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Pam2CSK4 (HB3086)
Description:TLR2/6 activator. Induces potent NF-κB activation and cytokine production.
Pam3CSK4 (HB3428)
Description:TLR1/TLR2 agonist and potent NF-κB activator. Induces cytokine production.
Paroxetine hydrochloride (HB0478)
Description:Potent, selective serotonin reuptake inhibitor. Selective GRK2 inhibitor.
Purity:>99%
Anti-Parvalbumin antibody ValidAbâ„¢ (HB6457)
Description:Antibody to Parvalbumin - calcium binding protein used as a marker for an inhibitory interneuron subtype. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, RatPaxilline (HB1056)
Description:Potent, reversible, selective KCa channel inhibitor. Also SERCA inhibitor.
Purity:>98%