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Biological Data Biological description Enzyme inhibitor. Inhibits tyrosine protein kinase, phosphodiesterase and phospholipase A2. Inhibits L-type voltage-gated calcium channel inward currents and increases voltage-gated K+ channel currents. Shows antioxidant, neuroprotective, antidepressant, anxiolytic, antitumor, anti-asthma and vasodilator actions.
Solubility & Handling Storage instructions Room temperature
Solubility overview Soluble in DMSO (100 mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Chemical name 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H -1-benzopyran-4-one
Chemical structure
Molecular Formula C15 H10 O7
PubChem identifier 5280343
SMILES C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O
InChiKey REFJWTPEDVJJIY-UHFFFAOYSA-N
References for Quercetin References are publications that support the biological activity of the product
Enhancement of voltage-gated K+ channels and depression of voltage-gated Ca2+ channels are involved in quercetin-induced vasorelaxation in rat coronary artery. Hou X et al (2014) Planta Med 80(6) : 465-72. Quercetin acutely relaxes airway smooth muscle and potentiates β-agonist-induced relaxation via dual phosphodiesterase inhibition of PLCβ and PDE4. Townsend EA et al (2013) Am J Physiol Lung Cell Mol Physiol 305(5) : L396-403. Quercetin as an inhibitor of snake venom secretory phospholipase A2. Cotrim CA et al (2011) Chem Biol Interact 189(1-2) : 9-16. Tyrosine protein kinase activity in the DMBA-induced rat mammary tumor: inhibition by quercetin. Levy J et al (1984) Biochem Biophys Res Commun 123(3) : 1227-33.
![Quercetin [117-39-5] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0542.png "Quercetin [117-39-5]")
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