G protein coupled receptors
G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
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Nocodazole (HB3999)
Description:Mitosis inhibitor, widely used as a cell cycle synchronizing agent. Enhances HDR efficiency and increases Cas9-mediated gene editing frequencies.
Purity:>98%
Nω-Propyl-L-arginine hydrochloride (HB0466)
Description:Potent, selective nNOS inhibitor
Purity:>98%
NSC697923 (HB4001)
Description:Selective Ub-conjugating enzyme (E2) complex Ubc13-Uev1A inhibitor
Purity:>98%