Product overview

Name NU6102
Purity >98%
Description Potent CDK1 and CDK2 inhibitor
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Biological Data

Biological description Potent CDK1/cyclin B (IC50 = 9. 5 nM) and CDK2/cyclin A3 (IC50 = 5. 4 nM) inhibitor. 1'000-fold more potent than NU2058. Selective for CDK1 and CDK2 compared to CDK4/D1 (IC50 = 1. 6 µM), DYRK1A (IC50 = 0. 9 µM), PDK1 (IC50 = 0. 8 µM) and ROCK-II (IC50 = 0. 6 µM). Inhibits cell growth.

Solubility & Handling

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >98%
Molecular Weight 402.5
Chemical structure NU6102 [444722-95-6] Chemical Structure
CAS Number 444722-95-6
InChiKey OWXORKPNCHJYOF-UHFFFAOYSA-N
Appearance White to off-white solid