Potent CDK1/cyclin B (IC50 = 9. 5 nM) and CDK2/cyclin A3 (IC50 = 5. 4 nM) inhibitor. 1'000-fold more potent than NU2058. Selective for CDK1 and CDK2 compared to CDK4/D1 (IC50 = 1. 6 µM), DYRK1A (IC50 = 0. 9 µM), PDK1 (IC50 = 0. 8 µM) and ROCK-II (IC50 = 0. 6 µM). Inhibits cell growth.
Solubility & Handling
Storage instructions
+4°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.