GluN2C

Selective H₁ receptor inverse agonist

LKB1/AMPK activator. Also promotes neurogenesis.

Non-selective 5-HT₂ receptor antagonist. Shows activity at other receptors.

K_ir6 channel activator

NMDA receptor antagonist. Less active enantiomer of (+)-MK 801.

Potent, selective, non-competitive NMDA receptor antagonist

Selective K_v7.2 / K_v7.4 channel activator

Selective K_2P2.1 (TREK-1) and K_2P10.1 (TREK-2) activator

Covalent K_2P2.1 (TREK-1) modulator

Selective K_2P2.1 (TREK-1) and K_2P10.1 (TREK-2) activator