ML 213

Name: ML 213
Brand: Hello Bio
SKU: HB1064
Price: 151 USD
Availability: InStock

(HB1064)

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Technical documents: SDS CoA Datasheet

Product overview

Name

ML 213

Purity

>99%

Description

Selective K_v7.2 / K_v7.4 channel activator

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) References (3) Frequently bought together

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Images

ML 213 product vial image | Hello Bio

Biological Data

Biological description

Selective K_v7.2 and K_v7.4 channel activator (EC₅₀ values are 230 and 510 nM respectively). Exhibits >80-fold selectivity for K_v7.2 and K_v7.4 channels over other K⁺ channels. Displays vasorelaxant properties.

Solubility & Handling

Storage instructions

+4°C

Solubility overview

Soluble in DMSO (50mM) or ethanol (50mM)

Important

This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

More Info

Dilution

More Info

Chemical Data

Purity

>99%

Chemical name

N-(2,4,6-Trimethylphenyl)-bicyclo[2 .2.1]heptane-2-carboxamide

Molecular Weight

257.37

Chemical structure

Molecular Formula

C₁₇H₂₃NO

CAS Number

489402-47-3

PubChem identifier

3111211

SMILES

O=C(NC3=C(C)C=C(C)C=C3C)C1CC2CCC1C2

InChiKey

SIQGKPGBLYKQBB-UHFFFAOYSA-N

Technical guides

Understanding purity and quality - a guide for life scientists (159.4 KB)

References for ML 213

References are publications that support the biological activity of the product

Vasorelaxant effects of novel Kv 7.4 channel enhancers ML213 and NS15370.
Jepps TA et al (2014) Br J Pharmacol 171(19) : 4413-24.
Read more (PubMedID: 24909207)
Differential activation of vascular smooth muscle Kv7.4, Kv7.5, and Kv7.4/7.5 channels by ML213 and ICA-069673.
Brueggemann LI et al (2014) Mol Pharmacol 86(3) : 330-41.
Read more (PubMedID: 24944189)
Discovery, Synthesis, and Structure Activity Relationship of a Series of N-Aryl- bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener.
Yu H et al (2011) ACS Chem Neurosci 2(10) : 572-577.
Read more (PubMedID: 22125664)

Selective K_v7.2 / K_v7.4 channel activator

Order: HB1064
Pack	Price	Qty
10mg	$151
50mg	$641

ML 213

Product overview

Images

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for ML 213

Vasorelaxant effects of novel Kv 7.4 channel enhancers ML213 and NS15370.

Differential activation of vascular smooth muscle Kv7.4, Kv7.5, and Kv7.4/7.5 channels by ML213 and ICA-069673.

Discovery, Synthesis, and Structure Activity Relationship of a Series of N-Aryl- bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener.

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ML 213

Product overview

Images

ML 213 product vial image | Hello Bio

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for ML 213

Vasorelaxant effects of novel Kv 7.4 channel enhancers ML213 and NS15370.

Differential activation of vascular smooth muscle Kv7.4, Kv7.5, and Kv7.4/7.5 channels by ML213 and ICA-069673.

Discovery, Synthesis, and Structure Activity Relationship of a Series of N-Aryl- bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener.

About you

Tell us about your publication!

Captcha

About you

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New Products in this Area