Ionotropic glutamate receptors
Ionotropic glutamate receptors (NMDA, AMPA and Kainate receptors) are cation-selective tetramers formed by multimeric assemblies of subunits. AMPA receptors comprise of homomers or heteromers of GluA1, GluA2, GluA3 and GluA4 subunits. NMDA receptors are heteromic assemblies of GluN1, GluN2A, GluN2B, GluN2C, GluN2D, GluN3A and GluN3B. Kainate receptors can be expressed as homomers of GluK1, GluK2 or GluK3. Researchers can save up to 50% on potent & selective NMDA, AMPA and Kainate receptor antagonists, agonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.
View resources: Ionotropic Receptor Nomenclature Guide | NMDA Receptor Mini-Review | NMDAR Associated Proteins
View products:Â AMPA | Kainate | NMDA
SB 216763 (HB1272)
Description:Potent, selective cell permeable GSK-3 inhibitor. Maintains mESCs and promotes retinal stem cells proliferation.
Purity:>98%
SB 431542 (HB3555)
Description:Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.
Purity:>98%
SP600125 (HB2234)
Description:Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.
Purity:>98%
SU 5402 (HB3133)
Description:Potent FGFR and VEGFR inhibitor. Attenuates integrin β4-induced neural stem cell differentiation.
Purity:>95%
Thiazovivin (HB3240)
Description:Rock inhibitor. Improves hESCs survival and fibroblast reprogramming efficiency and iPSCs induction.
Purity:>97%
Troglitazone (HB2559)
Description:Potent, selective PPARγ agonist. Inhibits hematopoietic cell line growth.
Purity:>97%
ROCK inhibitor Y-27632 (HB2297)
Description:Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts.
Purity:>99%