Potent, selective PPARγ agonist with no activity at PPARα or PPARδ. Decreases insulin resistance and shows potent glucose-lowering effects. Also stimulates adipogenesis and induces cellcycle arrest and apoptosis in several cancer cell lines. Shows anti-diabetic and anti-inflammatory activity.
Solubility & Handling
Storage instructions
-20°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.