Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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    Description:

    Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).

    Purity:

    >98%

    Pack:
    10mg
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    50mg
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    $246
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  2. Pack:
    50mg
    Price:
    $40
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    250mg
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    $149
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    Pack:
    1g
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    $240
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  3. Description:

    Pan kinase inhibitor. Potently inhibits MEK1, Cdk1, Cdk2, Cdk3 and Cdk5 and GSK-3β.

    Purity:

    >97%

    Pack:
    250μg
    Price:
    $207
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    Pack:
    1mg
    Price:
    $689
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  4. IDR 1002 (HB8122)

    Description:

    Innate defence regulator peptide

    Pack:
    1mg
    Price:
    $172
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  5. Description:

    Tyrosine kinase inhibitor that targets BCR‑ABL, c‑KIT, and PDGFR kinases

    Purity:

    >98%

    Pack:
    100mg
    Price:
    $87
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  6. Imiquimod (HB3109)

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    Description:

    Toll-like receptor 7 (TLR7) agonist

    Purity:

    >98%

    Pack:
    100mg
    Price:
    $91
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    Pack:
    250mg
    Price:
    $179
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  7. Description:

    Water soluble Toll-like receptor 7 (TLR7) agonist. Stimulates cytokine production.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $29
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    Pack:
    50mg
    Price:
    $52
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    Pack:
    100mg
    Price:
    $77
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    Pack:
    250mg
    Price:
    $147
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  8. Pack:
    10mg
    Price:
    $66
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    50mg
    Price:
    $263
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  9. Pack:
    1mg
    Price:
    $123
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    Pack:
    5mg
    Price:
    $416
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