Tyrosine kinase inhibitor that targets BCR‑ABL, c‑KIT, and PDGFR kinases. It binds close to the ATP binding site to inhibit enzyme activity semi-competitively, leading to subsequent inhibition of downstream signaling pathways.
Shows anticancer actions and used in chronic myeloid leukemia research.
Shows antiviral actions against SARS-CoV and MERS-Cov in vitro. Recently investigated as part of COVID-19 compound repurposing.
Solubility & Handling
Solubility overview
Soluble in water (100mM) and DMSO (100mM)
Storage instructions
+4°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use
![Imatinib mesylate [220127-57-1] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb1943_1.png "Imatinib mesylate [220127-57-1]")
Understanding purity and quality - a guide for life scientists
