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Indinavir Sulfate

(HB7480)
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Technical documents: SDS CoA Datasheet

Product overview

Name Indinavir Sulfate
Purity >98%
Description Antiretroviral protease inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3)
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Biological Data

Biological description

Orally activ antiretroviral protease inhibitor which inhibits HIV-1 protease and suppresses HIV replication. It also induces glutathione export from astrocytes.

Recently investigated as part of COVID-19 compound repurposing.

Solubility & Handling

Storage instructions RT
Solubility overview Soluble in water (15 mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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More Info

Dilution

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More Info

Chemical Data

Purity >98%
Chemical name (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide sulphate salt
Molecular Weight 711.87
Chemical structure Indinavir Sulfate [157810-81-6] Chemical Structure
Molecular Formula C36H47N5O4.H2SO4
CAS Number 157810-81-6
PubChem identifier 5462355
SMILES CC(C)(C)NC(=O)[C@@H]1CN(CCN1C[C@H](C[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H]3[C@@H](CC4=CC=CC=C34)O)O)CC5=CN=CC=C5.OS(=O)(=O)O
InChi InChI=1S/C36H47N5O4.H2O4S/c1-36(2,3)39-35(45)31-24-40(22-26-12-9-15-37-21-26)16-17-41(31)23-29(42)19-28(18-25-10-5-4-6-11-25)34(44)38-33-30-14-8-7-13-27(30)20-32(33)43;1-5(2,3)4/h4-15,21,28-29,31-33,42-43H,16-20,22-24H2,1-3H3,(H,38,44)(H,39,45);(H2,1,2,3,
InChiKey NUBQKPWHXMGDLP-HZUPJJOCSA-N
Appearance White solid

References for Indinavir Sulfate

References are publications that support the biological activity of the product

  • HIV protease inhibitor nelfinavir inhibits replication of SARS-associated coronavirus

    Yamamoto et al (2004) Biochem Biophys Res Commun . 18(3) : 719-25
    Read more (PubMedID: 15144898)

  • Indinavir acutely inhibits insulin-stimulated glucose disposal in humans: a randomized, placebo-controlled study

    Grunfeld et al (2002) Clinical Trial 16(5) : F1-8
    Read more (PubMedID: 11964551)

  • Disposition of indinavir, a potent HIV-1 protease inhibitor, after an oral dose in humans

    Balani et al (1996) Clinical Trial 24(12) : 1389-94
    Read more (PubMedID: 8971147)

3 Item(s)

Related Products
Grouped product items
Order: HB7480
Pack PriceQty
10mg
$66
50mg
$263
Antiretroviral protease inhibitor
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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