Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 791-800 of 1076

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  1. Pack:
    500μg
    Price:
    $95
    Qty:
    Pack:
    5mg
    Price:
    $429
    Qty:
    Pack:
    10mg
    Price:
    $647
    Qty:
  2. Description:

    PTP inhibitor

    Purity:

    >95%

    Pack:
    10mg
    Price:
    $197
    Qty:
  3. Purmorphamine (HB3412)

    Description:

    Smo receptor agonist that activates the hedgehog pathway. Induces mesenchymal and iPSC differentiation.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $171
    Qty:
    Pack:
    25mg
    Price:
    $386
    Qty:
  4. Pyranonigrin A (HB4042)

    Description:

    Antioxidant compound

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $307
    Qty:
  5. Pyripyropene A (HB4044)

    Description:

    Highly specific acyl-coenzyme A cholesterol acetyltransferase 2 inhibitor

    Purity:

    >95%

    Pack:
    250μg
    Price:
    $179
    Qty:
    Pack:
    1mg
    Price:
    $538
    Qty:
  6. QNZ 46 (HB0541)

    Description:

    GluN2C/D selective, non-competitive NMDA receptor antagonist

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $458
    Qty:
  7. Description:

    Broad enzyme inhibitor

    Purity:

    >95%

    Pack:
    250mg
    Price:
    $39
    Qty:
    Pack:
    1g
    Price:
    $128
    Qty:
  8. Description:

    5-HT2 and D2 antagonist. Atypical antipsychotic.

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $132
    Qty:
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