Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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    Description:

    Synthetic glucocorticoid with potent anti-inflammatory actions. Induces hMSC differentiation. Apoptosis inducer. Water soluble and suitable for cell culture. 

    Purity:

    >98%

    Pack:
    100mg
    Price:
    $109
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  2. Diastovaricin I (HB3872)

    Description:

    Antibiotic with antitumor and antibacterial activity

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $197
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    Pack:
    5mg
    Price:
    $593
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  3. Pack:
    100mg
    Price:
    $34
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    Pack:
    1g
    Price:
    $92
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  4. Description:

    Fluorescent reagent.

    Pack:
    5mg
    Price:
    $148
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  5. Description:

    Potent antiviral compound

    Purity:

    >97%

    Pack:
    5mg
    Price:
    $382
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  6. Pack:
    50mg
    Price:
    $70
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    Pack:
    250mg
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    $214
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  7. Pack:
    10mg
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    $217
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  8. 2  Reviews
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    Description:

    Widely used solvent. Improves direct differentiation of pluripotent stem cells and used as a stem cell cryoprotectant

    Purity:

    >99.9%

    Pack:
    10mL
    Price:
    $38
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    Pack:
    50mL
    Price:
    $119
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    Pack:
    5x10mL
    Price:
    $128
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  9. Description:

    Potent, selective AMPK inhibitor. Promotes neural hPSCs differentiation and promotes cardiomyocyte differentiation in mESCs.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $209
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    Pack:
    50mg
    Price:
    $829
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  10. Description:

    Antibiotic. DNA topisomerase II inhibitor. Apoptosis inducer.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $123
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    Pack:
    50mg
    Price:
    $517
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