Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Daptomycin (HB4375)

    Description:

    Antibiotic. Protein, DNA and RNA inhibitor.

    Pack:
    10mg
    Price:
    $83
    Qty:
    Pack:
    50mg
    Price:
    $305
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  2. Description:

    RNA and DNA synthesis inhibitor. Antibiotic.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $118
    Qty:
    Pack:
    50mg
    Price:
    $246
    Qty:
  3. Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $153
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    Pack:
    10mg
    Price:
    $193
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    Pack:
    50mg
    Price:
    $806
    Qty:
  4. H2DCFDA (HB8322)

    Description:

    Fluorescent dye for ROS and oxidative stress detection. Used to measure redox state of a cell.

    Pack:
    100mg
    Price:
    $71
    Qty:
  5. Pack:
    100 tests
    Price:
    $132
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    Pack:
    300 tests
    Price:
    $264
    Qty:
  6. Description:

    Histone methyltransferase inhibitor. Enhances Oct4 expression in chemically-induced pluripotent stem cells.

    Purity:

    >98%

    Pack:
    500μg
    Price:
    $123
    Qty:
    Pack:
    1mg
    Price:
    $180
    Qty:
    Pack:
    5mg
    Price:
    $812
    Qty:
  7. Description:

    Specific DNA polymerase α inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $258
    Qty:
  8. Description:

    Selective α-mannosidase I inhibitor

    Pack:
    5mg
    Price:
    $134
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    Pack:
    25mg
    Price:
    $517
    Qty:
  9. Description:

    α-glucosidase inhibitor.

    Pack:
    10mg
    Price:
    $193
    Qty:
    Pack:
    50mg
    Price:
    $748
    Qty:
  10. Dexamethasone (HB2521)

    Description:

    Anti-inflammatory synthetic glucocorticoid. Induces hMSC differentiation. Apoptosis inducer.

    Purity:

    >98%

    Pack:
    100mg
    Price:
    $68
    Qty:
    Pack:
    1g
    Price:
    $317
    Qty:
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