Daptomycin

(HB4375)

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Product overview

Name Daptomycin
Alternative names LY 146032
Description Antibiotic. Protein, DNA and RNA inhibitor.
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Biological Data

Biological description

Antibiotic. Shows potent anti-bacterial activity against most gram-positive bacteria.

Disrupts the plasma membrane to induce rapid depolariztion which inhibits protein, DNA and RNA synthesis.

Solubility & Handling

Solubility overview Soluble in DMSO (100 mM) and water (20 mM)
Storage instructions -20°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Chemical name N-(1-Oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithinyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-?-oxo-benzene butanoic acid (13-4) lactone
Molecular Weight 1620.67
Molecular Formula C72H101N17O26
CAS Number 103060-53-3
PubChem identifier 16129629
SMILES CCCCCCCCCC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)NC3C(OC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC3=O)CCCN)CC(=O)O)C)CC(=O)O)CO)C(C)CC(=O)O)CC(=O)C4=CC=CC=C4N)C
InChiKey DOAKLVKFURWEDJ-RWDRXURGSA-N
Appearance Yellow