Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Antiproliferative compound

    Purity:

    >96%

    Pack:
    5mg
    Price:
    $386
    Qty:
  2. Pack:
    1mg
    Price:
    $275
    Qty:
  3. Calcein Blue (HB0721)

    Description:

    Fluorescent metal ion indicator

    Pack:
    1mg
    Price:
    $373
    Qty:
  4. Pack:
    10mg
    Price:
    $176
    Qty:
    Pack:
    50mg
    Price:
    $712
    Qty:
  5. Calphostin C (HB0160)

    Description:

    Potent, selective PKC inhibitor. Also antagonizes the Tcf/β-catenin complex

    Purity:

    >95%

    Pack:
    100μg
    Price:
    $232
    Qty:
    Pack:
    1mg
    Price:
    $1,176
    Qty:
  6. Calpinactam (HB3823)

    Description:

    Specific anti-mycobacterial

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $409
    Qty:
  7. Description:

    Antibody to Calretinin - calcium binding protein used as a marker for an inhibitory interneuron subtype. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.

    Host: Rabbit
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μL
    Price:
    $171
    Qty:
    Pack:
    100μL
    Price:
    $382
    Qty:
  8. Pack:
    100μg
    Price:
    $418
    Qty:
  9. Description:

    Serine protease inhibitor. Inhibits TMPRSS2 and partially blocks SARS-Cov2 entry in vitro.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    Qty:
    Pack:
    50mg
    Price:
    $152
    Qty:
  10. Description:

    Chirality inducing agent

    Purity:

    >98%

    Pack:
    1g
    Price:
    $21
    Qty:
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