Calmodulin (CaM) antagonist. Inhibits calmodulin-dependent phosphodiesterase (IC50 = 0.15 µM). Antagonises Ca2+-transporting ATPase calmodulin-induced activation (IC50 = 0.35 µM). Inhibits adenylyl cyclase, soluble fusion protein, ACIX and ACV-ACII fusion proteins. Blocks L-type calcium channels as well as voltage-dependent Na+ and K+ channel currents; increases intracellular calcium. Shows cytotoxic and apoptotic effects.
Solubility & Handling
Solubility overview
Soluble in DMSO (100mM) or ethanol (100mM)
Storage instructions
+4°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
![Calmidazolium Chloride [57265-65-3] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb0156.png "Calmidazolium Chloride [57265-65-3]")
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