Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Orlistat (HB4009)

    Description:

    Pancreatic, gastric and carboxylester lipase inhibitor

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $166
    Qty:
    Pack:
    250mg
    Price:
    $200
    Qty:
  2. Pack:
    100mg
    Price:
    $64
    Qty:
  3. PAC 1 (HB1291)

    Description:

    Procaspase-activating compound

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $584
    Qty:
  4. Palmarumycin C3 (HB4013)

    Description:

    Rasfarnesyltransferase inhibitor

    Purity:

    >97%

    Pack:
    5mg
    Price:
    $524
    Qty:
  5. Pack:
    10mg
    Price:
    $105
    Qty:
    Pack:
    50mg
    Price:
    $418
    Qty:
  6. Paxilline (HB1056)

    Description:

    Potent, reversible, selective KCa channel inhibitor. Also SERCA inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $153
    Qty:
  7. Pack:
    50mg
    Price:
    $534
    Qty:
  8. PD 0325901 (HB2240)

    Description:

    Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    Qty:
    Pack:
    2mg
    Price:
    $29
    Qty:
    Pack:
    5×2mg
    Price:
    $120
    Qty:
    Pack:
    10mg
    Price:
    $114
    Qty:
    Pack:
    50mg
    Price:
    $321
    Qty:
  9. PD 150,606 (HB4018)

    Description:

    Selective, cell permeable calpain inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $423
    Qty:
  10. Pack:
    1mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $103
    Qty:
    Pack:
    50mg
    Price:
    $462
    Qty:
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