Target

PKC inhibitor

HIF-1 formation inhibitor

Type A proanthocyanidine with many biological actions

Mitochondrial permeability transition pore (MPTP) activator

Potent, selective PKA inhibitor

Novel, potent and selective GRK2/GRK3 inhibitor

Highly potent, cell permeable γ-secretase inhibitor

Potent, selective, non-competitive γ-secretase inhibitor. Induces neuronal differentiation.

STAT3 inhibitor

Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.