Target

Potent, non-selective K_v1.3 channel blocker

K_ir6 channel activator

Selective K_v7.2 / K_v7.4 channel activator

Selective K_2P2.1 (TREK-1) and K_2P10.1 (TREK-2) activator

Covalent K_2P2.1 (TREK-1) modulator. Used with CAT335 as part of the CATKLAMP chemogenetic strategy.

Selective K_2P2.1 (TREK-1) and K_2P10.1 (TREK-2) activator

Potent, selective K_Ca1.1 channel activator

Potent, selective K_Ca1.1 channel activator

K_v11.1 channel activator

Potent, selective K_Ca3.1 / K_Ca2 channel subfamily activator