Hedgehog signaling

Endogenous gluococorticoid. MR and GR agonist.

Potent, selective 5-HT_1B receptor agonist

Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.

AMPA receptor positive allosteric modulator. Inhibits AMPAR desensitization.

Selective K_Ca2.2 / K_Ca2.3 activator

mGlu_1α / mGlu_5a agonist

Potent, selective neuronal nicotinic agonist

Orphan nuclear receptor DAF-12 ligand

Estrogen receptors (ER) agonist. Phytoestrogen.

Potent, selective μ-opioid receptor agonist