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Daidzein

(HB2488)
Publications (1)
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Product overview

Name Daidzein
Purity >98%
Description Estrogen receptors (ER) agonist. Phytoestrogen.
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews Publications (1) References (3) Frequently bought together
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Biological Data

Biological description Estrogen receptors (ER) agonist. Soy phytoestrogen and genistein analog. Also shows activity at PPARs. Shows both estrogenic/anti-estrogenic activity, induces apoptosis and anticancer effects. Active in vivo.

Solubility & Handling

Storage instructions -20°C (desiccate)
Solubility overview Soluble in DMSO (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1- benzopyran-4-one
Molecular Weight 254.24
Chemical structure Daidzein [486-66-8] Chemical Structure
Molecular Formula C15H10O4
CAS Number 486-66-8
PubChem identifier 5281708
SMILES C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O
InChi InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H
InChiKey ZQSIJRDFPHDXIC-UHFFFAOYSA-N
MDL number MFCD00016954

References for Daidzein

References are publications that support the biological activity of the product

  • Daidzein induced apoptosis via down-regulation of Bcl-2/Bax and triggering of the mitochondrial pathway in BGC-823 cells.

    Tang S et al (2013) Cell Biochem Biophys 65(2) : 197-202.
    Read more (PubMedID: 22926545)

  • Daidzein causes cell cycle arrest at the G1 and G2/M phases in human breast cancer MCF-7 and MDA-MB-453 cells.

    Choi EJ et al (2008) Phytomedicine 15(9) : 683-90.
    Read more (PubMedID: 18541420)

  • Isoflavone metabolites and their in vitro dual functions: they can act as an estrogenic agonist or antagonist depending on the estrogen concentration.

    Hwang CS et al (2006) J Steroid Biochem Mol Biol 101(4-5) : 246-53.
    Read more (PubMedID: 16965913)

3 Item(s)

Publications
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These publications cite the use of Daidzein purchased from Hello Bio:

  • Noradrenaline Modulates the Membrane Potential and Holding Current of Medial Prefrontal Cortex Pyramidal Neurons via β1-Adrenergic Receptors and HCN Channels.

    Grzelka et al (2017) Grzelka et al 11:341 : 2
    PubMedID: 29209170

1 Item

Grouped product items
Order: HB2488
Pack PriceQty
50mg
$67
Estrogen receptors (ER) agonist. Phytoestrogen.
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Hazardous: $35

Shipped on ice: $35

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